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Prescription Weight Loss Treatments: What Are Your Options in the Philippines?

Written by Weight Loss Team

Published 03/18/2025

Updated 06/19/2025

Losing weight can be a challenge, especially when diet and exercise alone aren’t enough. For many Filipinos struggling with obesity or weight-related health issues, prescription weight loss treatments can be an effective solution. But with so many options available, how do you know which one is right for you?

In the Philippines, several FDA-approved medications can help manage weight by reducing appetite, increasing metabolism, or altering how the body absorbs fat. However, weight loss medications are not a one-size-fits-all solution. They work best when combined with a healthy diet, regular exercise, and lifestyle modifications to ensure long-term success.

This guide breaks down the most effective prescription weight loss treatments, including GLP-1 medications, their benefits, potential risks, and what to consider before using them.

Who Should Consider Prescription Weight Loss Treatments?

Weight loss medications are not for everyone. They are typically prescribed for individuals who:

  • Have a body mass index (BMI) of 30 or higher (classified as obese).

  • Have a BMI of 27 or higher with weight-related conditions like diabetes, hypertension, or sleep apnea.

  • Have tried diet and exercise but have not achieved or maintained significant weight loss.

These medications should only be used under medical supervision, as they may have side effects or interactions with other drugs.

1. GLP-1 Medications: Ozempic, Wegovy, and Saxenda

GLP-1 receptor agonists are some of the most effective weight loss medications available today. They work by mimicking a hormone that regulates hunger and blood sugar levels.

How They Work

  • Delay stomach emptying, making you feel fuller for longer.

  • Reduce appetite and cravings.

  • Help regulate blood sugar levels, making them ideal for individuals with type 2 diabetes.

Common GLP-1 Medications in the Philippines

  • Ozempic (Semaglutide) – Originally a diabetes medication but now widely used for weight loss.

  • Wegovy (Semaglutide in higher doses) – Specifically approved for weight loss.

  • Saxenda (Liraglutide) – Also approved for weight management.

Effectiveness

A study published in the New England Journal of Medicine found that individuals taking semaglutide (Wegovy) lost an average of 15% of their body weight over 68 weeks.

Side Effects

  • Nausea

  • Vomiting

  • Diarrhea

  • Reduced appetite

These medications are usually administered via injection and require a doctor’s prescription and supervision.

2. Orlistat (Xenical): A Fat Blocker

Orlistat is one of the most widely available prescription weight loss medications in the Philippines. Unlike GLP-1 medications, it works by blocking fat absorption in the digestive system.

How It Works

  • Prevents about 30% of dietary fat from being absorbed.

  • Unabsorbed fat is eliminated through stool.

  • Helps with long-term weight management when combined with a reduced-calorie diet.

Effectiveness

A clinical review in the American Journal of Clinical Nutrition found that individuals taking Orlistat for one year lost an average of 5-10% of their body weight.

Side Effects

  • Oily stools

  • Frequent bowel movements

  • Gastrointestinal discomfort

To reduce side effects, patients must follow a low-fat diet while taking Orlistat.

3. Phentermine-Topiramate (Qsymia): Appetite Suppressant

Phentermine-Topiramate (sold as Qsymia in some countries) is a combination medication that reduces appetite and increases metabolism.

How It Works

  • Phentermine acts as a stimulant to suppress hunger.

  • Topiramate is a medication used for seizures and migraines but has been found to enhance weight loss effects.

Effectiveness

A study in the Lancet found that patients taking Phentermine-Topiramate lost an average of 8-10% of their body weight over 12 months.

Side Effects

  • Insomnia

  • Increased heart rate

  • Dry mouth

  • Dizziness

This medication is not yet widely available in the Philippines, but some doctors may prescribe similar appetite suppressants.

4. Contrave (Bupropion-Naltrexone): Targets Cravings

Contrave is a combination of Bupropion (an antidepressant) and Naltrexone (used for addiction treatment). Together, they reduce cravings and control appetite.

How It Works

  • Bupropion boosts dopamine levels, helping reduce food cravings.

  • Naltrexone affects brain pathways related to hunger and satiety.

Effectiveness

A study published in Obesity Reviews found that Contrave users lost 5-8% of their body weight over 56 weeks.

Side Effects

  • Nausea

  • Dizziness

  • Increased blood pressure

  • Insomnia

Contrave is not yet available in most Philippine pharmacies, but some doctors may prescribe alternatives.

Making the Right Choice: Consultation and Lifestyle Changes

Before taking any prescription weight loss medication, it’s essential to consult with a licensed healthcare provider who can assess your medical history and weight loss goals.

Combining Medication with Lifestyle Changes

Prescription medications work best when paired with:

  • A healthy, balanced diet

  • Regular physical activity (at least 150 minutes per week)

  • Stress management techniques

  • Consistent monitoring of progress

Are Prescription Weight Loss Treatments Worth It?

Prescription weight loss treatments can be highly effective, but they work best when combined with healthy lifestyle changes. They are not a quick fix but can support long-term weight management for individuals struggling with obesity or weight-related health risks.

Choosing the right prescription weight loss treatment depends on your health status, weight loss goals, and tolerance for potential side effects. Some medications work better for appetite control, while others target fat absorption or metabolic regulation.

Before starting any medication, it’s important to:

  • Speak with a healthcare provider to determine if prescription weight loss treatment is appropriate for you.

  • Understand the side effects and risks of each medication to make an informed decision.

  • Commit to lifestyle changes, as medications are most effective when combined with a healthy diet and regular exercise.

  • Monitor your progress, and adjust your approach as needed with the guidance of a doctor.

Weight loss is a journey that requires long-term commitment. Prescription treatments can help accelerate progress, but sustainable weight management always comes down to healthy habits and consistent effort. If you're considering medical assistance for weight loss, consult a qualified healthcare professional to explore the best options for your needs.

  • GLP-1 medications (Ozempic, Wegovy, Saxenda) are the most effective but may cause nausea.

  • Orlistat (Xenical) blocks fat absorption and requires a low-fat diet.

  • Phentermine-Topiramate and Contrave help with appetite suppression but may have stimulant-like side effects.

  • Consulting a licensed healthcare provider is essential to determine the best treatment for your needs.

If you’re considering prescription weight loss medications, consult with a doctor to find the safest and most effective option for you.



Weight Loss Team

Weight Loss Team

The &you Weight Loss Team combines medical science with personal care, guiding Filipinos through their weight loss journey with trusted medications, holistic support, and culturally relevant health expertise.

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Weight Loss Team
The articles and guides on Andyou.ph are written by the &you Weight Loss Team, a group of doctors, pharmacists, health coaches and content writers with expertise in obesity, metabolism, and Filipino nutrition. Their content reflects a commitment to evidence-based medicine, clinical accuracy, and practical guidance tailored to your everyday life. Our team includes board-certified physicians in obesity and internal medicine, clinical pharmacists trained in weight-loss pharmacology, and certified health coaches specializing in sleep, stress, and behavior change. They lead our trusted programs for GLP-1 medications like Semaglutide and Tirzepatide, which follow globally validated protocols. Clinical trials such as STEP 1 and SURMOUNT-1 show these medications can help people lose 15 to 21 percent of their body weight. But medication is just part of the journey. The &you team offers holistic care by addressing cravings, hormones, sleep, and stress, while providing continuous support, dose adjustments, side effect monitoring, and personalized lifestyle education. We treat weight loss as a medical journey, not a willpower problem. Our team is here to guide you with empathy, not judgment. In the Philippines, obesity is often overlooked or misunderstood, and we aim to change that through education and care that truly works. Whether you're managing PCOS, postpartum weight gain, or insulin resistance, we're here to walk with you every step of the way.