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Cialis® vs. Viagra®: Which one is right for you?

Published 12/09/2024

Updated 03/27/2025

What is Cialis and Viagra?

Both Cialis (tadalafil) and Viagra (sildenafil) are commonly prescribed medications for erectile dysfunction (ED), but they work differently and have distinct characteristics.

The choice between Cialis and Viagra often depends on your individual needs, preferences, and lifestyle.

Here's a comparison to help you determine which might be right for you: 

1. Duration of Action:

  • Cialis: One of the key differences is how long Cialis lasts. It can stay effective for up to 36 hours, which is why it’s often called the "weekend pill." This long duration means you don't have to time your dose as precisely, and it allows for more spontaneity.
  • Viagra: Viagra generally lasts about 4–6 hours, meaning you need to plan its use a bit more carefully and take it around 30 minutes to an hour before sexual activity. Best for you? If you want flexibility and spontaneity over a longer period, Cialis might be a better fit. If you're okay with timing your dose more precisely for shorter durations, Viagra may be sufficient2. Timing of Dosing: Cialis: Can be taken either as needed or daily. The daily dose (lower dose) allows for continuous effects and can be taken at any time of day. Viagra: Taken only as needed, about 30–60 minutes before sex.


Best for you? If you prefer a medication that works daily and doesn't require as much planning, Cialis might be a better choice. If you're only concerned about occasional sexual activity, Viagra could be more convenient.

3. Food Interactions:

  • Cialis: Can be taken with or without food, and food doesn’t affect its efficacy.
  • Viagra: Should be taken on an empty stomach for best results, as high-fat meals can delay its action.

Best for you? If you prefer not to worry about timing meals with medication, Cialis may be easier to incorporate into your routine.

4. Side Effects:

Both medications have similar side effects, including headaches, back pain, flushing, nasal congestion, and dizziness. However, some people report that one medication causes fewer side effects than the other.

Best for you? If you’ve tried one of these medications and experienced significant side effects, it might be worth trying the other. Some people find one works better for them with fewer issues.

5. Underlying Health Conditions:

  • Cialis: May be prescribed for other conditions, such as benign prostatic hyperplasia (BPH), in addition to ED.
  • Viagra: Primarily prescribed for erectile dysfunction, though it has also been used off-label for other conditions (such as pulmonary hypertension). Best for you? If you have both ED and symptoms of BPH (e.g., frequent urination or difficulty urinating), Cialis may be more appropriate.

6. Price and Insurance Coverage:

The cost can vary depending on your insurance and whether you're buying a brand-name or generic version.

Cialis (tadalafil) has a generic version, which can be more affordable. Viagra (sildenafil) also has a generic version available.

Best for you? If cost is a major factor, check whether your insurance covers either medication, or consider the generic versions of both drugs.

Ultimately, our doctors can help guide you based on your health, preferences, and response to the medications. If you're unsure, discussing both options is a good next step.

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