Here's what we'll cover

Home / Weight Loss

Ozempic Side Effects: What People in the Philippines Should Expect

Published 03/20/2025

Updated 03/28/2025

Ozempic (semaglutide) has been making waves as a revolutionary treatment for weight loss and type 2 diabetes. Originally designed to help regulate blood sugar levels, this GLP-1 receptor agonist has gained significant attention for its ability to promote weight loss in clinical and real-world settings. But with its rising demand in the Philippines, many Filipinos are asking: What are the side effects of Ozempic? Are they manageable, or do they outweigh the benefits?

This article breaks down what you need to know about Ozempic’s side effects, how they impact Filipinos specifically, and what you can do to minimize potential risks.

Common Side Effects of Ozempic

Like any medication, Ozempic comes with potential side effects. While most are mild and manageable, some may require medical attention. Here’s a breakdown of the most frequently reported side effects:

Gastrointestinal Issues

Nausea (most common, especially in the early weeks)
Vomiting
Diarrhea
Constipation
Stomach pain or bloating

A study published in The New England Journal of Medicine found that gastrointestinal symptoms were the most frequently reported side effects among Ozempic users, with nausea occurring in up to 20% of patients.

Appetite and Weight Changes

Decreased appetite (leading to weight loss)
Altered taste perception

According to the American Diabetes Association, Ozempic users experience appetite suppression as part of the drug’s mechanism, contributing to weight loss benefits.

Blood Sugar and Energy Levels

Fatigue or tiredness
Mild dizziness
Low blood sugar (especially for those also on diabetes medication)

Most of these side effects occur as the body adjusts to Ozempic and often lessen over time. However, managing them properly is key to maintaining comfort and effectiveness.

More Serious Side Effects: When to Be Concerned

While rare, some side effects of Ozempic can be more serious. It’s essential to recognize warning signs early and seek medical attention if necessary.

Pancreatitis

Severe stomach pain that radiates to the back
Persistent nausea and vomiting

The World Health Organization warns that GLP-1 receptor agonists like Ozempic have been linked to an increased risk of pancreatitis, particularly in patients with a history of pancreatic disorders.

Gallbladder Problems

Severe abdominal pain (upper right side)
Jaundice (yellowing of the skin or eyes)
Unexplained nausea and vomiting

Thyroid Tumors (Rare but Serious)

Lumps or swelling in the neck
Trouble swallowing
Hoarseness or persistent voice changes

Kidney Function Issues

Dehydration due to persistent vomiting or diarrhea
Reduced urine output

While these severe reactions are uncommon, staying aware of the signs can help Filipinos make informed decisions about their health.

Why Do Filipinos Experience Side Effects Differently?

Several factors influence how Filipinos react to Ozempic, including genetics, diet, and pre-existing health conditions.

Dietary Habits

The traditional Filipino diet is high in carbohydrates, sugar, and fried foods, which can affect how the body responds to Ozempic, particularly in terms of digestion and blood sugar regulation.

Lactose Sensitivity

Many Filipinos have some degree of lactose intolerance, which may contribute to gastrointestinal discomfort when taking Ozempic.

Prevalence of Diabetes and Obesity

With diabetes and obesity rates on the rise in the Philippines, more Filipinos may be prescribed Ozempic, increasing the importance of understanding its side effects.

How to Manage Ozempic Side Effects

1. Start with a Low Dose and Gradually Increase

Doctors usually begin with a lower dose of Ozempic and increase it gradually to help minimize nausea and other side effects.

2. Adjust Your Diet

Eat smaller, more frequent meals instead of large meals.
Avoid greasy, fried, or highly processed foods.
Stay hydrated to prevent dehydration from nausea or diarrhea.

3. Monitor Blood Sugar Levels

If you’re taking Ozempic for diabetes, check your blood sugar levels regularly to prevent hypoglycemia (low blood sugar).

4. Stay Active

Light physical activity, such as walking after meals, can aid digestion and help with nausea.

5. Communicate with Your Doctor

Regular check-ins with your doctor ensure that any severe side effects are addressed quickly. If side effects persist or worsen, a dosage adjustment or alternative medication may be needed.

Long-Term Safety of Ozempic: What Research Says

Long-term studies on Ozempic are ongoing, but current research suggests that it remains a safe and effective option for weight loss and diabetes management. According to a study published in The New England Journal of Medicine , Ozempic significantly reduces HbA1c levels and supports weight loss without major adverse reactions in most patients.

Additional research from the American Diabetes Association confirms that while nausea and gastrointestinal discomfort are the most reported issues, the benefits of improved metabolic health often outweigh these drawbacks. However, long-term monitoring is recommended, especially for those with a history of pancreatitis or thyroid disorders.

When to Seek Medical Attention

If you experience any of the following, seek immediate medical help:

Persistent nausea and vomiting leading to dehydration
Severe stomach pain or bloating
Swelling in the neck or trouble swallowing
Symptoms of low blood sugar (dizziness, excessive sweating, confusion)
Sudden and unexplained weight loss beyond expectations

Should You Take Ozempic? Factors to Consider

Who Should Consider Ozempic?

Individuals struggling with type 2 diabetes and in need of better glucose control.
Those looking for medical weight loss solutions under a doctor’s supervision.
Filipinos at risk of cardiovascular disease who may benefit from Ozempic’s protective effects.

Who Should Avoid Ozempic?

Individuals with a history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2.
Those with severe kidney or liver disease.
Pregnant or breastfeeding women (limited safety data available).

Is Ozempic Worth It for Filipinos?

For many Filipinos, Ozempic offers a promising solution for weight loss and diabetes management. While side effects are common, they are often manageable with the right approach. The key is awareness, preparation, and close communication with a healthcare provider.

What’s Next?

If you’re considering Ozempic, talk to a healthcare professional to determine if it’s right for you. For more science-backed health and wellness guides, check out our latest blogs at andyou.ph.