Why Your Annual Physical Exam Is Missing These 12 Biomarkers

&you Labs Team

Written by &you Labs Team

Updated August 7, 2026

Have you ever finished a yearly physical exam, gotten the "all clear," and still felt off? There is usually a reason. The standard yearly physical exam in the Philippines is built for basic clearance and catching obvious disease. It is not built to show how your body is really doing day to day.

Here is the result: a typical physical exam checks 8 to 10 biomarkers. It skips 12 that often matter more. Here is what gets missed, why, and what you can do about it.

Quick answer

A standard physical exam in the Philippines usually includes a CBC, a urine test, fasting glucose, a basic cholesterol panel, ALT, AST, creatinine, BUN, and uric acid. It usually skips HbA1c, fasting insulin, ApoB, hs-CRP, vitamin D, B12, ferritin, Free T3, Free T4, lipoprotein(a), GGT, and homocysteine. Many of these skipped markers matter more for your long-term health than what gets tested.

What a standard physical exam actually covers

Most employer or HMO-paid physical exams in the Philippines include:

  • CBC. Blood cell counts.
  • Urine test. A check on kidney and bladder health.
  • Chest X-ray. Screens for TB and lung problems.
  • Fasting blood sugar. Your glucose right now, nothing more.
  • Cholesterol panel. Total cholesterol, LDL, HDL, and triglycerides.
  • Liver enzymes. ALT and AST, sometimes.
  • Kidney basics. Creatinine, BUN, and uric acid.
  • Hepatitis B and sometimes HIV screening. Often required by an employer.
  • Sometimes TSH. Usually only in premium packages.

This panel is built to catch active diabetes, serious cholesterol problems, advanced organ disease, and infection. It is not built to catch an early drift in your health. It also misses the quiet markers that shift first.

The 12 biomarkers that get skipped

1. HbA1c

Your average blood sugar over 3 months. This catches pre-diabetes and quiet metabolic problems that a single glucose reading can miss. Healthy target: under 5.4%.

2. Fasting insulin

The earliest sign of insulin resistance, often high for years before glucose rises. Healthy target: under 8 µIU/mL.

3. ApoB

A protein found on every particle that can clog your arteries. More accurate than LDL alone, especially if you have high triglycerides. Healthy target: under 90 mg/dL.

4. Lipoprotein(a)

A genetic risk factor. It raises your heart attack and stroke risk on its own. You only need to test it once in your life. Most people in the Philippines have never had it measured. Healthy target: under 30 mg/dL.

5. hs-CRP

A marker of ongoing inflammation. A result that stays high raises your heart risk, even with normal cholesterol. Healthy target: under 1 mg/L.

6. Vitamin D (25-OH)

Deficiency is common in the region, even with a sunny climate. Indoor work, sunscreen, and pollution are the main reasons. It affects your bones, immune system, and mood. Healthy target: 40 to 60 ng/mL.

7. Vitamin B12

Supports your energy, nerves, and red blood cells. Low B12 causes fatigue, brain fog, and nerve problems. It is becoming more common as more people eat plant-based diets. Healthy target: 500 to 900 pg/mL.

8. Ferritin

Shows your iron stores. This drops before your hemoglobin does. A "normal" ferritin of 25 ng/mL in a woman can still mean low iron. Healthy target: 50 to 150 ng/mL.

9. Free T3

One of the active thyroid hormones your body actually uses. Standard exams typically test only TSH and skip this.

10. Free T4

The other active thyroid hormone. A "normal" TSH with low Free T3 or Free T4 explains a lot of unexplained fatigue and stubborn weight.

11. GGT

Shows stress on your liver and bile ducts. Sensitive to alcohol, some medicines, and metabolic problems. Often the earliest liver marker to shift with fatty liver disease. Healthy target: under 25 U/L.

12. Homocysteine

Relates to blood vessel and cell health. A high level is linked to heart and brain risk. It usually improves with more folate and B12 if it is elevated.

Why these markers usually get skipped

Three reasons explain most of it.

  1. Cost. Insurance and HMO plans pay per test. The cheapest panel that meets clearance rules tends to win.
  2. Disease versus trend. A standard exam is built to catch a disease you already have. Trend markers like HbA1c or ApoB can feel "extra" under that mindset.
  3. Old habits. Standard panels were set years ago. They have not caught up with newer evidence on early detection.

None of these are good reasons for your long-term health. They are just how the system works.

What you can do about it

Here are three options, from least to most effort.

Option 1: Ask your doctor to order them

At your next physical exam or a follow-up visit, ask for:

  • HbA1c
  • Fasting insulin
  • ApoB
  • hs-CRP
  • Vitamin D, B12, and ferritin
  • Free T3 and Free T4

You will likely pay out of pocket for these, since insurance rarely covers them.

Option 2: Book a self-pay panel

Self-pay labs let you order a full panel without a referral. A panel like &you Labs is built to cover many of these markers in one panel. Results come with both the standard range and the healthy target range, plus a doctor's interpretation.

Option 3: Combine both

Many people use a mix of both. Keep the employer-required exam for compliance. Run a fuller panel separately for your own health picture. The two reports work well together.

A sample year of testing

Here is a reasonable yearly plan if you want better visibility into your health.

  • Around your exam month: your standard employer physical exam.
  • Around the same time: a fuller panel that covers what the exam misses.
  • A few months later: retest any flagged markers, like vitamin D after supplements, or ALT after a lifestyle change.
  • Later in the year: an optional check-in on your metabolic markers if you are actively working on them.

If you are dealing with a specific concern, like fatigue or a family history of heart disease, test that group of markers more often.

Frequently asked questions

Are these 12 biomarkers really necessary if I feel fine?

Feeling fine is a poor way to judge your biomarkers. Many of the biggest problems cause no early symptoms. This includes pre-diabetes, low vitamin D, mild fatty liver, and an underactive thyroid. Testing catches these before symptoms show up.

Will my doctor order these if I ask?

Most doctors in the Philippines will. The usual barrier is cost, not medical disagreement. Insurance simply does not cover the extras. Bring a written list to your appointment.

Do I need a referral to order these tests myself?

For most self-pay labs, no. You can book a panel directly. Your results still come with a doctor's written interpretation.

Are any of these required by Philippine medical guidelines?

Some Philippine medical groups recommend HbA1c, ApoB, and a full thyroid panel for people at higher risk. A standard physical exam often skips these recommendations in practice.

Key takeaways

  • A standard physical exam in the Philippines checks about 8 to 10 biomarkers. It skips 12 that often matter more for long-term health.
  • The biggest gaps are HbA1c, fasting insulin, ApoB, hs-CRP, vitamin D, B12, ferritin, and a full thyroid panel.
  • These markers catch a trend, the pattern that predicts disease years ahead. That is different from disease you already have.
  • You can close the gap by asking your doctor for the additions. You can also book a fuller panel yourself.
&you Labs Team
&you Labs Team

The &you Labs Team combines medical science with personal care. We help Filipinos understand their health markers with blood work analysis that is easy to follow, whole person support, and health expertise built for Filipino life.

This content is provided for educational purposes only and is not intended as medical advice. It should not replace professional medical consultation, diagnosis, or treatment. Please consult a qualified healthcare provider to discuss the risks and benefits of any treatment option.