Important Info about Compounded Tirzepatide
Important Safety Information for Compounded Tirzepatide
What is Compounded Tirzepatide?
Compounded Tirzepatide is a prescription injectable medication used to improve blood sugar control in adults with type 2 diabetes. It may also support weight loss in adults with a body mass index (BMI) of 30 or higher, or 27 and above with weight-related health conditions, when used alongside a reduced-calorie diet and increased physical activity.
This medication is not a substitute for insulin and is not approved for the treatment of type 1 diabetes or diabetic ketoacidosis.
Who should not use Compounded Tirzepatide?
Do not use Compounded Tirzepatide if you:
- Have a personal or family history of medullary thyroid carcinoma (MTC).
- Have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).
- Are allergic to tirzepatide or any of its ingredients.
If you’re unsure about your medical history, consult your healthcare provider before starting this treatment.
How is Compounded Tirzepatide used?
Tirzepatide is administered as a once-weekly subcutaneous injection in your abdomen, thigh, or upper arm. You may self-inject at home or follow your doctor’s instructions for administration.
If you miss a dose, take it as soon as possible within 4 days. If more than 4 days have passed, skip the missed dose and resume your regular dosing schedule. Do not double up on doses.
Store the medication in the refrigerator. If kept at room temperature, follow your pharmacist’s instructions for safe storage. Dispose of used needles in a designated sharps container.
What should I tell my healthcare provider before using Compounded Tirzepatide?
Be sure to inform your healthcare provider about:
- Any history of thyroid cancer, pancreatitis, kidney or liver issues, or gallbladder disease.
- Whether you are pregnant, planning to become pregnant, or breastfeeding.
- All medications you are currently taking—including insulin, sulfonylureas, over-the-counter drugs, and supplements—as some combinations may increase the risk of hypoglycemia.
What are the most serious side effects of Compounded Tirzepatide?
Although rare, serious side effects can occur. Stop using the medication and seek immediate medical care if you experience:
- Thyroid tumors: Symptoms may include a lump in the neck, trouble swallowing, or persistent hoarseness.
- Pancreatitis: Severe abdominal pain, with or without vomiting, may indicate inflammation of the pancreas.
- Severe hypoglycemia: Particularly if combined with insulin or sulfonylureas—symptoms include shakiness, confusion, dizziness, or excessive sweating.
- Kidney problems: Dehydration from persistent nausea, vomiting, or diarrhea can lead to kidney damage.
- Severe allergic reactions: Such as rash, itching, swelling, or difficulty breathing.
What are the most common side effects?
The most common side effects include nausea, diarrhea, vomiting, constipation, and abdominal discomfort. These are usually temporary and improve as your body adjusts to the medication. If these symptoms persist or worsen, consult your doctor.
Additional safety information
Compounded Tirzepatide is not a standalone solution for weight management. It works best when combined with a healthy diet and exercise regimen.
This medication has not been shown to reduce the risk of heart attacks, strokes, or other cardiovascular events in people without type 2 diabetes. Never share injection pens or needles—doing so can transmit infections.
Reporting side effects
To report side effects in the Philippines, contact the Philippine Food and Drug Administration (FDA) through their Adverse Drug Reaction (ADR) Reporting System or call +63 2-8809-5596.
For full prescribing information and additional details, visit the Philippine FDA website.
